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Index > Protein center > ZP3(Gene name) > Chicken
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  • ZP3 (Gene name),
  • Zona pellucida sperm-binding protein 3 (Protein name ),  ZP3_CHICK from NCBI database.
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  • Gene name:
    ZP3(ZPC);
    Protein name:
    Zona pellucida sperm-binding protein 3;
    Alternative:
    Zona pellucida C protein;Sperm receptor;Zona pellucida glycoprotein 3(Zp-3);
    Organism:
    Chicken (Gallus gallus). 
    General Annotation
    Sub Unit:
    Homodimer. Forms higher oligomers, once its C-terminus has been proteolytically removed. Forms heterooligomers with other zona pellucida glycoproteins.
    Function:
    Component of the zona pellucida, which mediates species-specific sperm binding. Directly binds to sperm. Important for egg fertilization.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    437
    Sequence:
    50:
    MQGGRVVLGL | LCCLVAGVGS | YTPWDISWAA | RGDPSAWSWG | AEAHSRAVAG | 
    100:
    SHPVAVQCQE | AQLVVTVHRD | LFGTGRLINA | ADLTLGPAAC | KHSSLNAAHN | 
    150:
    TVTFAAGLHE | CGSVVQVTPD | TLIYRTLINY | DPSPASNPVI | IRTNPAVIPI | 
    200:
    ECHYPRRENV | SSNAIRPTWS | PFNSALSAEE | RLVFSLRLMS | DDWSTERPFT | 
    250:
    GFQLGDILNI | QAEVSTENHV | PLRLFVDSCV | AALSPDGDSS | PHYAIIDFNG | 
    300:
    CLVDGRVDDT | SSAFITPRPR | EDVLRFRIDV | FRFAGDNRNL | IYITCHLKVT | 
    350:
    PADQGPDPQN | KACSFNKARN | TWVPVEGSRD | VCNCCETGNC | EPPALSRRLN | 
    400:
    PMERWQSRRF | RRDAGKEVAA | DVVIGPVLLS | ADPGAVGQQE | EGGDGAAVMV | 
    437:
    PSVGTGLVCV | AVAVALAAVG | VAVGIARKGC | TRTSAAV
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    Pfam:
    Uniprot:
     
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    ELISA Kit for Chicken Zona pellucida sperm-binding protein 3
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    ELISA Kit for Chicken Zona pellucida sperm-binding protein 3
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    ELISA Kit for Chicken Zona pellucida sperm-binding protein 3
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    ELISA Kit for Chicken Zona pellucida sperm-binding protein 3
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    CLIA Kit for Chicken Zona pellucida sperm-binding protein 3
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    CLIA Kit for Chicken Zona pellucida sperm-binding protein 3
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    CLIA Kit for Chicken Zona pellucida sperm-binding protein 3
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    CLIA Kit for Chicken Zona pellucida sperm-binding protein 3
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    CLIA Kit for Chicken Zona pellucida sperm-binding protein 3
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    Polyclonal Antibody for Chicken Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Chicken Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Chicken Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Chicken Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Chicken Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Chicken Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Chicken Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Chicken Zona pellucida sperm-binding protein 3
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    P11951Rb-h
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Chicken Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Chicken Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Chicken Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Chicken Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Chicken Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Chicken Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Chicken Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Chicken Zona pellucida sperm-binding protein 3
    Protein for Chicken Zona pellucida sperm-binding protein 3
    Protein for Chicken Zona pellucida sperm-binding protein 3
    Protein for Chicken Zona pellucida sperm-binding protein 3
    Protein for Chicken Zona pellucida sperm-binding protein 3
    Protein for Chicken Zona pellucida sperm-binding protein 3
    Protein for Chicken Zona pellucida sperm-binding protein 3
    Protein for Chicken Zona pellucida sperm-binding protein 3
    Protein for Chicken Zona pellucida sperm-binding protein 3

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    References
    1. 1.
      "A 42-kDa glycoprotein from chicken egg-envelope, an avian homolog of the ZPC family glycoproteins in mammalian Zona pellucida. Its first identification, cDNA cloning and granulosa cell-specific expression."
      Takeuchi Y. , Nishimura K. , Aoki N. , Adachi T. , Sato C. , Kitajima K. , Matsuda T.
      Eur. J. Biochem.260:736-742(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 21-35; 47-66 AND 265-280;SUBCELLULAR LOCATION;GLYCOSYLATION;TISSUE SPECIFICITY
      strain: White leghorn.
      tissue: Ovarian follicle.
    2. 2.
      "Testing for adaptive evolution of the female reproductive protein ZPC in mammals, birds and fishes reveals problems with the M7-M8 likelihood ratio test."
      Berlin S. , Smith N.G.
      BMC Evol. Biol.5:65-65(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Gallus gallus zona pellucida C protein gene."
      Kono Y. , Matsuda T.
      Submitted (1999-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Liver.
    4. 4.
      "Interaction of sperm with purified native chicken ZP1 and ZPC proteins."
      Bausek N. , Ruckenbauer H.H. , Pfeifer S. , Schneider W.J. , Wohlrab F.
      Biol. Reprod.71:684-690(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
    5. 5.
      "Insights into egg coat assembly and egg-sperm interaction from the X-ray structure of full-length ZP3."
      Han L. , Monne M. , Okumura H. , Schwend T. , Cherry A.L. , Flot D. , Matsuda T. , Jovine L.
      Cell143:404-415(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 53-383 OF MUTANT GLN-159;FUNCTION;GLYCOSYLATION AT ASN-159 AND THR-168;SUBUNIT;SUBCELLULAR LOCATION;IDENTIFICATION BY MASS SPECTROMETRY;MUTAGENESIS OF CYS-58; CYS-90; ARG-142; CYS-152; ASN-159; THR-168; GLU-196; CYS-229; PRO-235; PRO-241; CYS-251; TYR-292; CYS-313; CYS-332; CYS-334; CYS-335; CYS-340 AND 359-ARG--ARG-362;DISULFIDE BONDS
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